LCMS Testing of Xylazine

LCMS Testing of Xylazine

Xylazine, an approved animal tranquilizer in the U.S., acts as a sedative and analgesic for veterinary use [1]. It is an α-2 adrenoreceptor agonist, detected in the unregulated drug supply throughout the eastern United States and Canada [2]. It has been detected in 91% of fentanyl/ heroin samples in Philadelphia and showed its presence in national […]

Fentanyl Immunoassay is a Vital Tool in the Battle Against Opioid Crisis

Fentanyl Immunoassay

Fentanyl is a synthetic opioid that is 50 to 100 times more potent than morphine. It is used to treat patients with severe pain after surgery, especially those who are physically tolerant to other opioids [1]. However, it is often abused illegally and mixed with other drugs, which can result in dangerous respiratory depression. The […]

BNP vs NT-proBNP

BNP vs NT-proBNP

Heart failure (HF) is a complex clinical syndrome affecting 6.2 million people in the United States [1]. The diagnosis of heart failure is challenging as patients usually present non-specific symptoms, which are often shared by other diseases. Both B-type natriuretic peptide (BNP) and the N-terminal pro BNP (NT-proBNP) are widely used as biomarkers to diagnose […]

Fentanyl Overdose Increase and the Opiate Epidemic in the USA

Fentanyl Overdose Increase

What is Fentanyl? Fentanyl is a synthetic opioid that was first developed in 1959 and introduced in the 1960s as an intravenous anesthetic. Fentanyl was also used for pain management as a transdermal patch in cancer patients. It is 50-100 times stronger than morphine. As an illicit drug, fentanyl is added to heroin to increase potency. […]