NEXT-GENERATION SEQUENCING

Next-Generation Sequencing

Breakthrough Innovations in NGS

Next-generation sequencing (NGS) is a technology for determining the sequence of DNA or RNA to study genetic variation associated with diseases or other biological phenomena.

Learn about the advantages and efficiencies in groundbreaking NGS Panel Design and Library Preparation.

Targeted DNA technology enables detection of somatic and germline
variants with a broad range of panel offerings.

CONTACT FOR QUOTE

 

Integrated Sample to Result Interpretation


Sample Extraction
and
Preparation

Library
Preparation

NGS Run

Compatible with Illumina and Ion Torrent Sequencing Platforms


Secondary
Data Analysis

Bioinformatics
and
Result
Interpretation

TECHNOLOGY ADVANTAGES

What are the benefits of the Next-Generation Sequencing technology for your laboratory?

LIBRARIES READY IN JUST 6 HOURS

Sample to sequencing-ready library in as little as 6 hrs, instead of standard ~12 hrs.
Incubation time: 4 hrs. Hands-on time: 2 hrs.

BETTER READ EFFICIENCY

With higher library complexity, there is no need to waste reads on PhiX. All reads are for samples only.

INCREASED PANEL SENSITIVITY

Ready to confidently call low variant allele frequency (VAF) and reveal biological context for variants, including actionable information.

UNIQUE MOLECULAR INDICES (UMI)

UMIs tag each molecule within the sample prior to amplification.
This corrects for PCR and sequencing-induced artifacts, generating high confidence in the variant detection results.

 

UNIQUE DUAL
INDICES (UDI)

UDIs ensure the accurate demultiplexing of sample data.
This results in decreased levels of index hopping and read misassignment.

 

Single Primer Extension (SPE)

SPE is a unique technology increasing cost efficiency.
By producing better uniformity of coverage across all targeted regions of interest, SPE reduces the per sample read requirement during sequencing.

 

ENZYMATIC CLEAN UP

Enzymatic Clean ups substitute bead clean ups. It makes the workflow more streamlined and time efficient.

HEREDITARY CANCER RESEARCH PANELS

Genes implicated in hereditary solid tumor and hematological malignancies research.



COMPREHENSIVE
CANCER

PROSTATE
CANCER

BREAST and
OVARIAN
CANCER

COLORECTAL
CANCER

PANCREATIC
CANCER


HEMATOLOGIC
MALIGNANCIES

FOCUS ONCOLOGY PANELS

Focus Oncology Panels include genes and variants that are actionable and known to be implicated in solid tumor and hematological malignancies research.



COMPREHENSIVE
CANCER

BRAIN
CANCER

BREAST
CANCER

COLORECTAL
CANCER

LUNG
CANCER

MYELOID
NEOPLASMS

 

Hereditary Disease Panels / Custom panels

Genetic NGS panels for hereditary disease. Custom panels available for any specific laboratory needs.

  • Comprehensive Hereditary Carrier
  • Cardiovascular Hereditary Panel
  • Parkinson’s, Alzheimer, Dementia (PAD) Hereditary Panel
  • Diabetes / Obesity Hereditary
  • Jewish Hereditary Carrier
  • Cystic Fibrosis
  • Custom panels designed to individual lab requirement

CONTACT US

To learn more about the Standard and Custom NGS Panels, for technical assistance and price quotation,
fill out the form below and one of our expert representatives will contact you.

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