Product Description
The TOX A/B QUIK CHEK ® test is a rapid enzyme immunoassay that uses antibodies specific for toxins A and B of C. difficile.
The device contains a Reaction Window with two stripes. One stripe is a test line specific for toxins A and B. The other stripe is the control line.
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TOX A/B QUIK CHEK:
- Detects C. difficile toxins A and B in fecal specimens
Results should be considered in conjunction with the patient history.
Result Indicators
- Proper test performance is indicated by the formation of a blue line at the control side (C) of the Reaction Window.
- A positive result is indicated by the formation of a blue line at the test side (T) of the Reaction Window.
Materials provided
• Membrane Devices –25 pouches, each containing 1 device
• Diluent (14 mL) – Buffered protein solution containing 0.02% thimerosal with
graduated dropper assembly*
Danger H360 – May damage fertility or the unborn child.
H412 – Harmful to aquatic life with long lasting effects.
P201, P202, P273, P280, P308+P313, P405, P501
• Wash Buffer (10 mL) – A buffered solution containing 0.02% thimerosal with
graduated dropper assembly*
• Substrate (3.5 mL) – Solution containing tetramethylbenzidine
• Conjugate (2 mL) – Mouse monoclonal antibody specific for toxin A coupled
to horseradish peroxidase and goat polyclonal antibody specific for toxin B
coupled to horseradish peroxidase in a buffered protein solution containing
0.02% thimerosal (contains mercury)
• Positive Control (1 mL) – Antigen in a buffered protein solution
• Disposable plastic transfer pipettes – 50 (graduated at 25 µL, 400 µL and 500 µL)
| Product Name | Suggested CPT Code | Analyte(s) Detected | Format | Time to Result | Fecal Sample Type |
| TOX A/B QUIK CHEK | 87324 | Toxins A&B | Rapid EIA | < 30 min | Fresh fecal sample (unpreserved) / Cary Blair / C&S |
FEATURES & BENEFITS
- Easy to interpret
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Highly sensitive and specific
- Results in approximately 30 minutes
PRODUCT DETAILS
You may place order by giving us a call
| Catalog Number | Description | Units of Measurements |
| TL30394 | TOX A/B QUIK CHEK | 25 Tests/Kit |
DOCUMENTATION AND VIDEOS
Brochure, package inserts and additional literature provided below:
TOX A/B QUIK CHEK Poster Presentations
Comparative Evaluation of Six Commercially Available Assays for the Detection of Clostridium difficile Toxins in Fecal Specimens
Comparison of the C. difficile TOX A/B QUIK CHEK® with commercial C. difficile A+B ELISAs
American Society for Microbiology meeting, May 2006, Orlando, FL
Comparison of the TOX A/B QUIK CHEK® to tissue culture assay and to a commercial A+B ELISA for the detection of Clostridium difficile toxins in fecal specimens
American Society for Microbiology meeting, May 2006, Orlando, FL
A New Rapid Test for Detecting Clostridium difficile Toxins A and B in Fecal Specimens
American Society for Microbiology meeting, June 2005, Atlanta, GA
C. DIFFICILE DIAGNOSTICS
Clostridium difficile is the major cause of nosocomial diarrhea and pseudomembranous colitis
C. difficile infection usually occurrs when the normal microflora of the intestinal tract is altered or killed by antibiotics. Once C. difficile growth begins, toxins A and B are produced, causing diarrhea and colitis.
Toxigenic strains of C. difficile carry the genes encoding the toxins. The disease results from the toxins that the organism produces. C. difficile produces two main toxins, toxin A and toxin B. Toxin A is a weakly cytotoxic enterotoxin. C. difficile also produces toxin B, which is a cytotoxin. Toxin B can be detected by the tissue culture assay. Toxigenic C. difficile strains produce both toxins or only toxin B.
The disease can be treated with antibiotics, but relapses are common.
