Product Description
The C. DIFF QUIK CHEK COMPLETE test is a rapid membrane enzyme immunoassay for the simultaneous detection of Clostridium difficile glutamate dehydrogenase antigen and toxins A and B in a single reaction well.
The test is to be used as an aid in the diagnosis of C. difficile disease.
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C. DIFF QUIK CHEK COMPLETE:
- Screens for the presence of C. difficile
- Detects C. difficile antigen and toxin
- Confirms the presence of toxins A and/or B
Results should be considered in conjunction with the patient history.
Result Indicators
- A blue line at the left (Ag) side of the Reaction Window indicates the presence of glutamate dehydrogenase.
- A blue line at the left (Ag) side and the right (Tox) side of the Reaction Window indicates the presence of glutamate dehydrogenase and C. difficile toxin.
Materials provided
• Membrane Devices – each pouch contains 1 device
• Diluent (22 mL per bottle) – Buffered protein solution with graduated dropper assembly (contains 0.05% ProClin® 300)
Signal Word: Warning
H317:May cause an allergic skin reaction
P261, P272, P280, P302, P352, P333, P313, P321, P362, P363, P364, P501
• Wash Buffer (12 mL per bottle) – Buffered solution with graduated dropper assembly (contains 0.05% ProClin® 300)
Signal Word: Warning
H317:May cause an allergic skin reaction
P261, P272, P280, P302, P352, P333, P313, P321, P362, P363, P364, P501
• Substrate (3.5 mL per bottle) – Solution containing tetramethylbenzidine
• Conjugate (2.5 mL per bottle) – Antibody specific for glutamate dehydrogenase coupled to horseradish peroxidase and antibodies specific for toxins A and B coupled to horseradish peroxidase in a buffered protein solution (contains 0.05% ProClin® 300)
Signal Word: Warning
H317:May cause an allergic skin reaction
P261, P272, P280, P302, P352, P333, P313, P321, P362, P363, P364, P501
• Positive Control (2 mL) – Antigen in a buffered protein solution
• Disposable plastic transfer pipettes – graduated at 25 µL, 100 µL, 200 µL, 300µL, 400 µL, and 500 µL
In Vitro Diagnostic Medic
| Product Name | Suggested CPT Code | Analyte(s) Detected | Format | Time to Result | Fecal Sample Type |
| C. DIFF QUIK CHEK COMPLETE | 87324 and 87449 | Toxins A&B GDH | Rapid EIA | < 30 min | Fresh fecal sample (unpreserved) / Cary Blair / C&S |
FEATURES & BENEFITS
- Easy to interpret
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Highly sensitive and specific
- Results in approximately 30 minutes
PRODUCT DETAILS
You may place order by giving us a call
| Catalog Number | Description | Units of Measurements |
| TL30525C | C. DIFF QUIK CHEK COMPLETE | 25 Tests/Kit |
| TL30550C | C. DIFF QUIK CHEK COMPLETE | 50 Tests/Kit |
DOCUMENTATION AND VIDEOS
Brochure, package inserts and additional literature provided below:
C. DIFF QUIK CHEK COMPLETE Poster Presentations
C. DIFF QUIK CHEK COMPLETE®
American Society of Microbiology meeting, May 2011, New Orleans, LA
Prevalence of Clostridium difficile in Fecal Samples from Inpatient and Outpatient Populations
American Society of Microbiology meeting, May 2011, New Orleans, LA
A New Rapid Combination Test for Clostridium difficile Antigen and Toxins A and B in Feces – Evaluation of the C. DIFF QUIK CHEK COMPLETE®
American Society for Microbiology meeting, May 2009, Philadelphia, PA
Comparison of the C. DIFF QUIK CHEK COMPLETE®, a Rapid Combination Test for Clostridium difficile GDH Antigen and Toxins A and B in Feces with Bacterial Culture and Cytotoxin Assay
American Society for Microbiology meeting, May 2009, Philadelphia, PA
Clinical Evaluation of a New Enzyme Immunoassay (C. DIFF QUIK CHEK COMPLETE®) for the Rapid and Simultaneous Detection of Clostridium-Glutamate Dehydrogenase and C. difficile Toxin A/B
American Society for Microbiology meeting, May 2009, Philadelphia, PA
Choosing C. difficile Diagnostics Wisely
Improper diagnosis of C. difficile can lead to patient harm
C. difficile diagnosis can be challenging. It is possible to be a carrier of C. difficile, meaning that the bacteria is present, but is not producing disease-causing toxins that make people sick.
It is important to properly differentiate people with a true C. difficile infection from C. difficile carriers. Treating C. difficile carriers may make people more susceptible to a true C. difficile infection. Antibiotic treatments for the initial infection may also be unnecessarily stopped.
There are three types of diagnostic tests for C. difficile :
Glutamate dehydrogenase (GDH) is the protein produced by all C. difficile bacteria, regardless of their toxin-producing ability. Testing for GDH is a good screening marker for C. difficile infection, but follow-up testing is necessary because we cannot tell from a GDH result alone if the strain can produce toxin, which makes patients sick. With a GDH-positive result alone, it is possible that the patient is simply a carrier.
Toxins A and B are produced by toxigenic strains of C. difficile and cause the symptoms of the infection. Toxin results more closely correlate to disease state and clinical outcomes than other testing options, but testing is not sensitive enough to be used as a standalone test.
Molecular (PCR) testing is a very sensitive method of identifying whether the C. difficile bacteria can make toxin but does not indicate whether toxin is actually present in the patient sample.
What do the guidelines say?
Because so many people are C. difficile carriers, the Infectious Disease Society of America (IDSA), Society for Healthcare and Epidemiology of America (SHEA), the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), and the American College of Gastroenterology (ACG) all suggest using a toxin test to help differentiate patients with active disease from those who are simply carriers.
